Recent Advances of Chemical Definition of Cell Culture Media and Excipients for Virus and Viral Vector Manufacturing

A vital step in the manufacturing of vaccines and viral vector-based cell and gene therapies is virus production. Historically, virus production relies heavily on undefined and highly variable raw material for cell-based platforms to be successful. Yet due to supply chain constraints, poor reproducibility, and safety concerns attributed to potential adventitious agents present in serum …

Poster 2021: Application of Biomass Probe with Chemically Defined Media in iCELLis

Utilization of classical adherent formats in large scale viral vector manufacturing can have significant setbacks due to the lack of scalability of production vessels typically used at small scale. The iCELLis fixed bed bioreactor has emerged as an enabling technology to efficiently scale adherent-based processes in a controlled and highly integrated environment. This technology has …