Use of Gas Permeable Rapid Expansion (G-Rex®) Culture ware with Chemically Defined Media for Simplistic and Robust T Lymphocyte Expansion

Introduction As immune cell therapies continue to show promising clinical efficacy, advancements in manufacturing platforms must continue in parallel in order to enhance process control, definition, and ultimately, process yield. The single use Gas Permeable Rapid Expansion (G-Rex) vessel offers a practical, robust, and cost-effective solution for immune cell expansion scale up and scale out. …

Improving Vaccine Development, Performance, and Stability with Recombinant HSA Excipient

Exbumin rHSA Improved Performance and Stability in Vaccine Development   Abstract A key aspect of vaccine production is maintaining stability and function of the final product, including sustained potency and viral titer.  Indeed, this knowledge has driven various preservation strategies, such as lyophilization, temperature control, and localized constitution for use.  However, these are only partial …