Optibumin ^® 20 – Recombinant human albumin

Product Description

Optibumin® 20 is the highest-purity recombinant human serum albumin (rHSA) available, designed as a direct replacement for serum-derived HSA in biomanufacturing, cell therapy, drug formulation, and assisted reproductive technologies. This chemically defined, animal-origin-free, GMP-grade product ensures batch-to-batch consistency, pathogen safety, and regulatory compliance, making it ideal for advanced bioprocessing applications.

Manufactured in the United States under ISO 9001:2015-certified, cGMP-compliant conditions, Optibumin 20 is free from stabilizers and preservatives, offering exceptional purity, low lipid content, and superior protein stability. Its high mercaptoalbumin (Cys34 free thiol) content makes it particularly well-suited for drug conjugation, solubilization, and formulation stability.

Supplied as a 20% liquid, Optibumin 20 is optimized for seamless integration into cell therapy workflows, recombinant protein formulations, and biopharmaceutical manufacturing.

Advantages

• Highest Purity & Performance
  • Highest purity albumin available – free from stabilizers and preservatives.
  • Low lipid content and high mercaptoalbumin (Cys34 free thiol) – ensuring superior small-molecule solubilization and drug conjugation.
  • Lowest product-related high molecular weight impurities – maximizing protein integrity and bioavailability.
• Animal-Origin-Free Assurance
  • 100% chemically defined and animal-origin-free (AOF) – eliminating regulatory risks associated with plasma-derived HSA.
  • Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
  • Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with ethical and regulatory standards.
• Manufactured in the United States
  • Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
  • Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
  • Consistent global supply, free from plasma donation limitations.
• Ready-to-Use 20% Liquid Format
  • Supplied as a sterile, 20% liquid solution, eliminating the need for reconstitution.
  • Designed for high-performance biomanufacturing, ensuring seamless integration into closed-system workflows.
  • Long-term stability and scalability for high-volume production needs.

Applications

• Cell Therapy & Biomanufacturing
  • Enhances cell therapy processing buffers and formulations, ensuring optimal cell viability and stability.
  • Used in cell expansion and cryopreservation for regenerative medicine applications.
  • Provides a consistent, high-purity protein source for closed-system biomanufacturing workflows.
• Drug Conjugation & Solubilization
  • High mercaptoalbumin (Cys34 free thiol) content enhances drug stability, small-molecule solubilization, and targeted drug delivery.
  • Supports bioconjugation strategies for antibody-drug conjugates and protein therapeutics.
• Recombinant Protein & Vaccine Formulation
  • Stabilizes biologic drug formulations, reducing aggregation and loss of bioactivity.
  • Ensures batch-to-batch consistency for protein-based vaccine production.
• Stem Cell Expansion & Regenerative Medicine
  • Optimized for Mesenchymal Stem Cell (MSC), induced Pluripotent Stem Cell (iPSC), and Embryonic Stem Cell (ESC) culture.
  • Provides a defined, animal-free alternative for long-term expansion and differentiation studies.
• In Vitro Fertilization (IVF) & Assisted Reproduction
  • Ultra-low lipid content improves embryo culture conditions and enhances developmental outcomes.
  • Provides a serum-free alternative to plasma-derived albumin, ensuring higher consistency and safety.

Technical Specifications

• Formulation: Sterile, ready-to-use 20% liquid solution
• Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
• Quality Assurance:
  • Fully recombinant and animal-origin-free production system
  • Stringent quality control processes ensure high batch-to-batch consistency
• Regulatory Compliance & Safety:
  • cGMP-compliant manufacturing
  • Plasma-free, pathogen-free, and chemically defined
  • Aligned with regulatory expectations for biopharmaceutical, regenerative medicine, and drug formulation applications

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