Leukemia Inhibitory Factor

Product Description

InVitria’s Leukemia Inhibitory Factor (LIF) is a recombinant, animal-origin-free cytokine engineered for optimal performance in stem cell culture applications. Commonly used to replace feeder cells in mouse embryonic stem cell (mESC) culture, our LIF is designed to maintain pluripotency and support self-renewal, ensuring consistent and reproducible cell growth. With the lowest endotoxin levels and highest purity among commercial LIF products, InVitria’s LIF provides an unparalleled solution for researchers demanding both quality and reliability.

Advantages

• Superior Purity and Low Endotoxin:
  • Produced using advanced recombinant technology, our LIF achieves exceptional purity levels.
  • Demonstrates the lowest endotoxin levels on the market, minimizing the risk of cell stress and ensuring optimal culture conditions.
• Animal-Origin-Free Assurance:
  • Manufactured entirely free from animal components using a non-animal, non-human host system.
  • All raw materials, equipment, and packaging are certified animal-origin-free, aligning with ethical sourcing practices and regulatory standards.
• Manufactured in the United States:
  • Produced in a tertiary-level, ISO 9001:2015 certified facility, ensuring rigorous quality control and traceability throughout the entire manufacturing process.
  • Complete supply and manufacturing chain is owned and operated by InVitria, ensuring consistency and reliable supply.
• Ready-to-Use Format:
  • Supplied as a sterile liquid formulation, saving valuable time by eliminating the need for reconstitution and reducing the risk of contamination.
  • Streamlined application for feeder-free culture systems and other critical cell culture protocols.

Applications

• Stem Cell Culture:
  • Ideal for maintaining pluripotency in mouse embryonic stem cell (mESC) cultures.
  • Supports feeder-free systems, offering a clean, reproducible alternative to traditional feeder cells.
• Pluripotency Maintenance:
  • Ensures high cell viability and consistent cell behavior by preventing spontaneous differentiation.
• Regenerative Medicine and Research:
  • Provides a reliable reagent for developmental biology studies, tissue engineering, and preclinical research requiring consistent cytokine performance.

Technical Specifications

• Formulation: Ready-to-use sterile liquid
• Manufacturing: Produced in a state-of-the-art, ISO 9001:2015 certified facility in the USA
• Quality Assurance:
  • Fully recombinant and animal-origin-free production system
  • Stringent quality control processes ensure high batch-to-batch consistency
• Safety:
  • 500-fold lower bacterial endotoxin compared to traditional E. coli-derived LIF
  • Designed to minimize immunogenicity and enhance cell culture reliability

Why Choose InVitria’s LIF?

InVitria’s LIF stands out as a like-kind replacement for traditional feeder cells and other commercial LIF products by offering unmatched purity, safety, and performance. Our commitment to animal-origin-free production not only addresses ethical concerns but also eliminates common issues such as endotoxin contamination and batch variability. Whether you are engaged in basic stem cell research, developmental biology, or advanced regenerative medicine, our LIF delivers the consistency and reliability you need to drive breakthrough research.