Using Recombinant Transferrin in the Expansion of Hematopoietic Stem Cells

Introduction: A growing number of clinical cases have provided strong proof of concept that hematopoietic stem-cell (HSC) therapies are potential treatments of blood cancers and many other debilitating diseases that were once thought to be incurable [1]. A critical tool to enable development of these therapies is expansion of HSCs in vitro [2]. However, supplementation …

T Regulatory Cells, The Next T Cell Frontier?

Recently I had the opportunity to attend the Treg Summit in Boston to listen to the ground-breaking clinical and preclinical research in re-balancing the immune system in the context of autoimmunity and organ transplant via the use of polyclonal or antigen-induced T regulatory cells. Overall, this cell therapy holds immense promise as evidenced by both preclinical …

Exploring the Latest Research and Opportunities in T-reg Therapy

Worldwide, researchers and industry leaders are improving health outcomes for patients by utilizing the multi-functional efficacy of regulatory t cells to develop novel therapies and disease treatments. Regulatory T cells, commonly referred to as ‘T-regs’, play a critical role in maintaining order in the human immune system by regulating and suppressing excessive inflammation. Given the therapeutic …

ASGCT 2019: Remarkable Milestones and Achievements in Cell and Gene Therapy

The American Society of Gene & Cell Therapy (ASGCT) held their 22nd annual meeting in Washington D.C. last week from April 29th through May 2nd bringing together a record number of over 3,400 attendees to share and discuss the remarkable work going on to advance this field. With 23 Scientific Symposia and 1000 abstracts presented …