InVitria: Solving the Vaccine Supply Challenge

Right now is an exciting time for vaccine science, with an unprecedented level of attention, resources, and testing being directed at the effort to control the COVID-19 pandemic. In this post, we share a new video and provide additional information to explain the role that InVitria’s recombinant human protein products play in accelerating the vaccine …

SARS-CoV2 and Influenza: A Double Threat

While we fight SARS-CoV-2, we must not turn our back on influenza As of this writing, the SARS-CoV-2 virus has infected at least 15.5 million people worldwide and resulted in at least 632,000 deaths. While extreme public health measures such as testing, contact tracing, school closures, travel restrictions, stay-at-home orders, social distancing, and compulsory masking, …

High-Performance Production of Viral Vectors for Cell and Gene Therapy Using OptiPEAK HEK293t Complete Media

HEK293t cells are an indispensable tool for the production of the viral vectors at the heart of cell and gene therapy technology. To introduce a way to improve performance, consistency, and safety of your HEK293-based production InVitria’s team released a new video that talks about our serum-free chemically defined media product, OptiPEAK HEK293t Complete Media.

Recombinant Virus Platforms are Out in Front in the Race to Develop Vaccines Against SARS-CoV-2 and COVID-19 Disease

SARS-CoV-2 continues to circulate the globe, causing widespread illness, loss of life , and far-reaching societal and economic disruption. Public health measures like stay-at-home and safer-at-home have been successful in checking the virus’s geometric growth curve, and treatments are in development. However, epidemiologists generally agree that achieving “herd immunity” through a safe and effective vaccine is …

Stabilizing Virus with Albumin to Improve Yield

Workflow Summary: Expand virus-producing cells to desired confluency. Remove growth medium and add the desired virus to be expanded (virus or plasmid DNA). Add Exbumin (Product Number: 777HSA097S) to the expression media and allow virus to propagate. Harvest culture and determine virus titer by preferred method. Here, a general protocol is described for the addition …

Controlling Impurities in Cell Culture Media

Originally Published by GEN, written by K. John Morrow Jr., PhD From its initial development back in the 1950s, cell culture media development has been plagued by impurities, often present in small quantities, difficult to characterize, and trace back to their origins. Classically, culture media have required the addition of animal serum, which serves a …

Reconstitution of Cellastim S for Cell-Culture Applications

Workflow Summary: Human serum albumin (HSA) has been identified as a powerful tool for the expansion of many cell types in vitro [1]. HSA is a multifaceted protein capable of binding many different types of molecules [2]. HSA therefore plays diverse roles in cell biology, acting as an antioxidant to improve health of cells by binding to reactive …

BioInnovation on Parade: Philly Stands Proud for BIO 2019!

Last week was the annual Biotechnology Industry Organization (BIO) annual convention in Philadelphia where medical innovations were abundant and showed remarkable promise. More than 17,000 delegates representing government, academia, and non-profit research institutes joined more than 4,000 companies in the City of Brotherly Love. The delegates share a common commitment to improve the quality and …