Author: Invitria

Use of Gas Permeable Rapid Expansion (G-Rex®) Culture ware with Chemically Defined Media for Simplistic and Robust T Lymphocyte Expansion

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Introduction As immune cell therapies continue to show promising clinical efficacy, advancements in manufacturing platforms must continue in parallel in order to enhance process control, definition, and ultimately, process yield. The single use Gas Permeable Rapid Expansion (G-Rex) vessel offers a practical, robust, and cost-effective solution for immune cell expansion scale up and scale out. …

Solving the Vaccine Supply Challenge

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Right now is an exciting time for vaccine science, with an unprecedented level of attention, resources, and testing being directed at the effort to control the COVID-19 pandemic. In this post, we share a new video and provide additional information to explain the role that InVitria’s recombinant human protein products play in accelerating the vaccine …

SARS-CoV2 and Influenza – Double Threat

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While we fight SARS-CoV-2, we must not turn our back on influenza As of this writing, the SARS-CoV-2 virus has infected at least 15.5 million people worldwide and resulted in at least 632,000 deaths. While extreme public health measures such as testing, contact tracing, school closures, travel restrictions, stay-at-home orders, social distancing, and compulsory masking, …

High-Performance Production of Viral Vectors for Cell and Gene Therapy Using OptiPEAK HEK293t Complete Media

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HEK293t cells are an indispensable tool for the production of the viral vectors at the heart of cell and gene therapy technology. To introduce a way to improve performance, consistency, and safety of your HEK293-based production InVitria’s team released a new video that talks about our serum-free chemically defined media product, OptiPEAK HEK293t Complete Media. …

Recombinant Virus Platforms are Out in Front in the Race to Develop Vaccines Against SARS-CoV-2 and COVID-19 Disease

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SARS-CoV-2 continues to circulate the globe, causing widespread illness, loss of life , and far-reaching societal and economic disruption. Public health measures like stay-at-home and safer-at-home have been successful in checking the virus’s geometric growth curve, and treatments are in development. However, epidemiologists generally agree that achieving “herd immunity” through a safe and effective vaccine is …

Controlling Impurities in Cell Culture Media

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From its initial development back in the 1950s, cell culture media development has been plagued by impurities, often present in small quantities, difficult to characterize, and trace back to their origins. Classically, culture media have required the addition of animal serum, which serves a nutritional function, but also may absorb and bind up trace impurities …

BioInnovation on Parade: Philly Stands Proud for BIO 2019!

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Last week was the annual Biotechnology Industry Organization (BIO) annual convention in Philadelphia where medical innovations were abundant and showed remarkable promise. More than 17,000 delegates representing government, academia, and non-profit research institutes joined more than 4,000 companies in the City of Brotherly Love. The delegates share a common commitment to improve the quality and …

Explore the Latest Developments in T-reg Research and Clinical Application

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Recently I had the opportunity to attend the Treg Summit in Boston to listen to the ground-breaking clinical and preclinical research in re-balancing the immune system in the context of autoimmunity and organ transplant via the use of polyclonal or antigen-induced T regulatory cells. Overall, this cell therapy holds immense promise as evidenced by both preclinical …