Recombinant Albumin Enhances Lentiviral Vector Stability During Downstream Processing
Lentiviral vectors (LVVs) remain one of the most widely used gene delivery systems for ex vivo cell therapy manufacturing, including CAR-T workflows, and are increasingly being explored for in vivo gene delivery applications. However, enveloped viral particles are highly sensitive to manufacturing-related stress during downstream processing. Operations such as tangential flow filtration (TFF), sterile filtration, …