Lentivirus Production Protocol in Serum-Free Conditions – How To Improve Transfection Efficiency and Titer Yield

Lentivirus Production in Serum-Free, Chemically Defined Conditions   Introduction Viral vector-based gene therapies are promising candidates in the treatment of rare, genetic diseases due to the natural ability of viruses to transfer genetic content into target cells. Lentivirus (LV) is a propitious mechanism of genetic delivery due to the low immunogenicity of the virus, the …

Emergence of Blood-Free Recombinant Human Albumin

Emergence of Blood-Free rHSA Albumin is a naturally occurring protein in animals and humans responsible for numerous cellular functions and is integral to the manufacturing of biopharmaceuticals. Various benefits of albumin inclusion in upstream manufacturing, downstream processing, and final formulation applications will be discussed in detail but can be briefly summarized as: Serves as an …