Lacromin^® – Recombinant human holo-lactoferrin

Product Description

Lacromin® is a high-purity recombinant human lactoferrin (rLF) designed to enhance cell growth, improve viability, and protect against apoptosis in cell culture applications. By activating cellular signaling pathways similar to Insulin-Like Growth Factor (IGF), Lacromin provides a chemically defined, serum-free alternative to traditional lactoferrin sources, optimizing growth conditions for CHO, HEK, primary, and pluripotent cell types.

Manufactured in an ISO 9001:2015-certified, cGMP-compliant facility in the United States, Lacromin ensures batch-to-batch consistency, regulatory compliance, and pathogen-free safety, making it ideal for biopharmaceutical production, cell therapy, and regenerative medicine.

Advantages

• Optimized for Serum-Free, Animal-Origin-Free Cell Culture
  • Fully recombinant, blood-free human lactoferrin, providing a stable and controlled supplement for cell culture.
  • Activates IGF-like signaling, enhancing cell proliferation and survival.
  • Prevents apoptosis in select cell types, improving viability and long-term culture success.
• Animal-Origin-Free Assurance
  • 100% chemically defined and animal-origin-free (AOF) – eliminating batch variability and regulatory risks associated with plasma-derived lactoferrin.
  • Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
  • Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with ethical and regulatory standards.
• Manufactured in the United States
  • Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
  • Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
  • Batch-to-batch consistency for reliable integration into cGMP cell culture workflows.
• Ready-to-Use Lyophilized Format
  • Supplied as a lyophilized powder, providing long-term stability and easy reconstitution.
  • Flexible formulation to support a wide range of cell culture applications.
  • Eliminates variability associated with serum-derived lactoferrin, enabling chemically defined media development.

Applications

• Cell Culture & Bioproduction
  • Enhances CHO and HEK cell proliferation, supporting biopharmaceutical and vaccine production.
  • Improves cell viability in chemically defined, serum-free media.
• Stem Cell Expansion & Regenerative Medicine
  • Supports pluripotent and primary cell cultures, ensuring high viability and growth rates.
  • Provides a defined, animal-free alternative for long-term cell culture and differentiation studies.
• Immune Cell Culture & Therapeutic Development
  • Enhances immune cell survival, reducing apoptosis in T cell and NK cell cultures.
  • Supports cellular activation and expansion in immunotherapy applications.
• Gene Therapy & Vaccine Production
  • Stabilizes cell cultures used for viral vector production, optimizing yields and process efficiency.
  • Ensures greater consistency in biomanufacturing workflows.

Technical Specifications

• Formulation: Lyophilized recombinant human lactoferrin
• Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
• Quality Assurance:
  • Fully recombinant and animal-origin-free production system
  • Stringent quality control processes ensure high batch-to-batch consistency
• Regulatory Compliance & Safety:
  • cGMP-compliant manufacturing
  • Plasma-free, pathogen-free, and chemically defined
  • Aligned with regulatory expectations for biopharmaceutical, regenerative medicine, and vaccine production applications

Why Choose Lacromin?

Lacromin is a high-performance alternative to serum-derived lactoferrin, offering unparalleled purity, stability, and regulatory compliance. Whether used for cell therapy, biopharmaceutical manufacturing, or regenerative medicine, Lacromin provides a safe, scalable, and animal-free solution for industrial and research applications.

See the Terms page for more information about the trademarks and patents that cover this product.