Optiferrin® – Recombinant human transferrin
The most effective way to deliver iron in cell culture without any oxidative reactions or cell damage caused by other iron sources.
Name | Price | Qty | |
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$351.72
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$2,177.16
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Product Description
Optiferrin® is a high-purity recombinant human transferrin (rTf), designed as a chemically defined, blood-free alternative to human holo transferrin for cell culture, stem cell expansion, and bioproduction applications. Engineered to deliver equivalent or superior performance to plasma-derived transferrin, Optiferrin provides unmatched regulatory advantages, safety, and consistency, making it ideal for serum-free and animal-free media formulations.
Manufactured in an ISO 9001:2015-certified, cGMP-compliant facility in the United States, Optiferrin ensures batch-to-batch consistency, pathogen safety, and scalability for research and industrial applications.
Advantages
- Optimized for Serum-Free, Animal-Origin-Free Cell Culture
- Fully recombinant, blood-free human transferrin – ensuring consistent performance without batch variability.
- Equivalent to human holo transferrin in supporting cell growth, proliferation, and iron homeostasis.
- Improves cell viability and metabolic activity in a wide range of cell culture applications.
- Animal-Origin-Free Assurance
- 100% chemically defined and animal-origin-free (AOF) – eliminating risks associated with plasma-derived transferrin.
- Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
- Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with regulatory and ethical standards.
- Manufactured in the United States
- Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
- Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
- Batch-to-batch consistency for reliable integration into cGMP bioproduction workflows.
- Ready-to-Use Lyophilized Format
- Supplied as a lyophilized powder, providing long-term stability and easy reconstitution.
- Flexible formulation to support a wide range of cell culture applications.
- Eliminates variability associated with plasma-derived transferrin, enabling chemically defined media development.
Applications
- Cell Culture & Bioproduction
- Supports CHO, HEK, VERO, and other mammalian cell lines, optimizing biopharmaceutical and vaccine production.
- Enables serum-free and chemically defined media for more consistent, reproducible results.
- Stem Cell Expansion & Regenerative Medicine
- Enhances iron regulation and metabolic activity in induced pluripotent stem cells (iPSC), mesenchymal stem cells (MSC), and embryonic stem cells (ESC).
- Supports long-term stem cell maintenance and differentiation without reliance on animal components.
- Gene Therapy & Vaccine Production
- Essential for virus propagation and recombinant protein expression, ensuring optimal iron homeostasis in cell culture.
- Improves yield and stability of viral vectors, supporting AAV and lentiviral production.
- T Cell & Primary Cell Culture
- Enhances immune cell proliferation and viability in T cell, NK cell, and primary cell cultures.
- Provides a defined, serum-free alternative for cell therapy applications.
Technical Specifications
- Formulation: Lyophilized recombinant human transferrin
- Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
- Quality Assurance:
- Fully recombinant and animal-origin-free production system
- Stringent quality control processes ensure high batch-to-batch consistency
- Regulatory Compliance & Safety:
- cGMP-compliant manufacturing
- Plasma-free, pathogen-free, and chemically defined
- Aligned with regulatory expectations for biopharmaceutical, regenerative medicine, and vaccine production applications
Why Choose Optiferrin?
Optiferrin is a high-performance alternative to plasma-derived transferrin, offering unparalleled purity, consistency, and regulatory compliance. Whether used for cell culture, biopharmaceutical manufacturing, or regenerative medicine, Optiferrin provides a safe, scalable, and animal-free solution for industrial and research applications.
See the Terms page for more information about the trademarks and patents covering this product.
Published Research Citing Optiferrin
Optiferrin is cited in 15+ peer-reviewed publications. The papers below are among the most frequently cited and include references to InVitria distributor part numbers as well as the Sigma-Aldrich catalog number T3705 (Optiferrin):
Full bibliography available upon request. Contact us for the complete publication list.