Month: July 2025

In Memory of Dr. William J. Rutter (1927–2025)

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We are deeply saddened by the passing of Dr. William J. Rutter—a visionary scientist, mentor, entrepreneur, and close friend to many at InVitria. He passed away on July 11, 2025, at the age of 97. Few scientists have shaped modern biotechnology as deeply as Dr. Rutter. His research laid the groundwork for recombinant insulin, genetically …

ITS-Animal-Free™ Supplementation for iPSC Expansion and Pluripotency: A Platform Approach for Serum-Free Cell Expansion

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Overview This application note evaluates the use of ITS Animal-Free™ (ITS AF)—a recombinant, animal-origin-free supplement containing insulin, transferrin, and selenium—for serum-free expansion of human induced pluripotent stem cells (iPSCs). The study demonstrates that ITS AF supports robust iPSC proliferation and maintains high levels of Oct4, Sox2, and Nanog expression, performing comparably to a leading competitor …