Optimizing Antibody Production in Animal-Free Media with the Supplementation of Recombinant Human Albumin (Cellastim™)
Abstract Due to the increased risk of transmitting infectious agents, antibody production is moving away from the use of animal-derived components in bioproduction. The switch to animal-free cell culture media often results in less performance which is evident in longer doubling time, lower peak cell density and reduced antibody titer. We evaluated recombinant human albumin …