Month: June 2025

Safe, Consistent Iron Delivery in Serum-Free Systems with Optiferrin® Recombinant Transferrin

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EXECUTIVE SUMMARY Efficient iron delivery is essential for cell growth and viability in vitro. Transferrin is widely used in cell culture media to fulfill this role. However, serum-derived transferrin poses challenges including batch variability, pathogen transmission risk, and regulatory complexity. InVitria’s Optiferrin is a recombinant human transferrin produced in a non-mammalian expression system that overcomes …

Why Border Disruptions Threaten Blood-Derived Raw Materials—and What Biomanufacturers Can Do About It

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Reading time: 4 minutes What happens when your biologics pipeline depends on the reliability of an international border? For many manufacturers still using plasma-derived components like albumin or transferrin, that’s not a hypothetical. It’s baked into their supply chain. Across the U.S.–Mexico border, more than 50 plasma centers depend on daily crossings from Mexican nationals …

Low-DMSO Cryopreservation of MSCs with Optibumin 25 Recombinant Albumin

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EXECUTIVE SUMMARY This application note demonstrates the use of Optibumin® 25—an animal-origin-free recombinant HSA—for low-DMSO cryopreservation of UC-MSCs. Optibumin matched or outperformed blood-derived HSA, even at DMSO levels as low as 1%, supporting safer, regulatory-friendly workflows for cell therapy manufacturing. Key Highlights Maintains MSC viability at 1–2.5% DMSO Reduces apoptosis vs. no-albumin controls Performs comparably …