Recombinant Albumin as a Carrier Protein Improves Cytokine Recovery and Functional Stability at Dilute Concentrations

Audio Summary: Optibumin 25 Stabilizes High-Cost Cytokines Overview This application note evaluates the use of Optibumin® 25, a recombinant, animal-origin-free human serum albumin (rHSA), as a carrier protein to stabilize dilute cytokine formulations commonly used in cell culture and cell therapy workflows.The study demonstrates that Optibumin 25 significantly improves cytokine recovery by reducing losses due …

Variability and Failed Lots: The Hidden Quality Control Challenge of Serum & Serum-Derived Products

Reading time: 4 minutes Share this article:   The biopharmaceutical industry faces a critical quality control challenge: the inherent variability of serum and plasma-derived products. While traditionally relied upon for cell culture, blood-derived albumin introduces significant lot-to-lot inconsistencies in protein heterogeneity, growth factor content, and biochemical profiles. These variations directly impact manufacturing success, particularly in …