Recombinant Human Albumin Supports Weekend-Free hiPSC Culture and Protein-Free Cardiac Differentiation Presented at ISSCR by Davi Lyra-Leite (BMEM Bio), Mark Stathos and Elliott Renft (InVitria), and Paul W. Burridge (Northwestern University Feinberg School of Medicine). The Problem Weekend-free hiPSC media change schedules save labor, but they have been reported to reduce subsequent differentiation efficiency. This …
Download App Note Here Executive Summary Lactoferrin (LF) is an iron-binding glycoprotein that is abundant in mammalian milk with established roles in iron homeostasis, anti-apoptotic protection, immune regulation, antimicrobial defense, antioxidant defense, neuroprotection, wound healing, and intestinal epithelial function. Lactoferrin exists in two forms: holo-lactoferrin (iron-saturated) and apo-lactoferrin (iron-free), with iron saturation influencing many of …
Download App Note Here Executive Summary Lentiviral vectors (LVVs) are widely used in cell and gene therapy manufacturing, but infectious titer is rapidly lost during transfer, storage and hold times in downstream processing. LVVs may be exposed to refrigerated or room temperature conditions for several hours before the next manufacturing step. In this study, purified …
