Optimizing Antibody Production in Animal-Free Media with the Supplementation of Recombinant Human Albumin (Cellastim™)

Abstract Due to the increased risk of transmitting infectious agents, antibody production is moving away from the use of animal-derived components in bioproduction. The switch to animal-free cell culture media often results in less performance which is evident in longer doubling time, lower peak cell density and reduced antibody titer. We evaluated recombinant human albumin …

ITSE Animal-Free Brochure

Introduction ITSE Animal-Free is a recombinant, animal-free media supplement used to improve cell performance. ITSE Animal-Free provides nutrients that are required for cell growth, and replaces other ITS or ITSE supplements that have components derived from animals. ITSE Animal-Free is an IgG-free sterile liquid, making it simple to use and allows easier purification of protein …

Accurate nanoelectrode recording of human pluripotent cell-derived cardiomyocytes for assaying drugs and modeling disease

Abstract The measurement of the electrophysiology of human pluripotent stem cell-derived cardiomyocytes is critical for their biomedical applications, from disease modeling to drug screening. Yet, a method that enables the high-throughput intracellular electrophysiology measurement of single cardiomyocytes in adherent culture is not available. To address this area, we have fabricated vertical nanopillar electrodes that can …