LIF – Guidelines for Use

Download the LIF Guidelines for Use to learn preparation, dosing, storage, and applications of recombinant human LIF. Animal-origin-free and chemically defined, it supports neural stem cell expansion and select pluripotent stem cell workflows.

OptiLeukin 2 – Guidelines for Use

Download the OptiLeukin 2 Guidelines for Use to learn preparation, dosing, storage, and applications of animal‑ and bacteria‑origin‑free recombinant IL‑2. Designed for GMP‑aligned workflows in T cell manufacturing and research.

Optibumin 25 – Guidelines for Use

Download the Optibumin® 25 Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant human serum albumin. Manufactured animal-origin-free, it supports safer, scalable workflows in cell therapy, vaccine, and biologics manufacturing.

In Memory of Dr. William J. Rutter (1927–2025)

We are deeply saddened by the passing of Dr. William J. Rutter—a visionary scientist, mentor, entrepreneur, and close friend to many at InVitria. He passed away on July 11, 2025, at the age of 97. Few scientists have shaped modern biotechnology as deeply as Dr. Rutter. His research laid the groundwork for recombinant insulin, genetically …

ITS-Animal-Free™ Supplementation for iPSC Expansion and Pluripotency: A Platform Approach for Serum-Free Cell Expansion

Overview ITS Animal-Free™ ITS Animal-Free (ITS AF), InVitria’s 100x cocktail of Insulin, Transferrin, and Selenium that is completely animal-origin-free, is essential for culture of all mammalian cell types including iPSCs. ITS AF can be conveniently supplemented into custom media formulations to replace the core components of serum. This reduces variability, eliminates safety and regulatory hurdles, …

Safe, Consistent Iron Delivery in Serum-Free Systems with Optiferrin® Recombinant Transferrin

Overview Efficient iron delivery plays a critical role in maintaining cell health, supporting proliferation, and maximizing therapeutic productivity. However, serum-derived transferrin introduces variability, regulatory risk, and the potential for contamination. This application note demonstrates how Optiferrin, a recombinant transferrin for iron delivery in serum-free media, provides a consistent and animal-origin-free alternative. It mirrors native transferrin …

Why Border Disruptions Threaten Blood-Derived Raw Materials—and What Biomanufacturers Can Do About It

Reading time: 4 minutes What happens when your biologics pipeline depends on the reliability of an international border? For many manufacturers still using plasma-derived components like albumin or transferrin, that’s not a hypothetical. It’s baked into their supply chain. Across the U.S.–Mexico border, more than 50 plasma centers depend on daily crossings from Mexican nationals …

Low-DMSO Cryopreservation of MSCs with Optibumin 25 Recombinant Albumin

Overview This application note demonstrates the use of Optibumin® 25—an animal-origin-free recombinant HSA—for low-DMSO cryopreservation of UC-MSCs. Optibumin matched or outperformed blood-derived HSA, even at DMSO levels as low as 1%, supporting safer, regulatory-friendly workflows for cell therapy manufacturing. Key Findings Maintains MSC viability at 1–2.5% DMSO Reduces apoptosis vs. no-albumin controls Performs as well …