Month: August 2025

Improved iPSC Cryopreservation with Optibumin 25: Enhanced Viability, Expansion, and Pluripotency

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Audio Summary: Improved iPSC Cryopreservation with Optibumin 25 EXECUTIVE SUMMARY Optibumin 25, InVitria’s recombinant animal-origin-free human serum albumin, improves post-thaw viability, expansion, and maintenance of pluripotency in iPSCs when used in cryopreservation formulations. Compared to plasma-derived HSA, Optibumin 25 demonstrated significantly greater improvements in cell health and survival. Additionally, supplementing CryoStor® CS5 with 5% Optibumin …

Superior Cryopreservation of T Cells in Low-DMSO, Animal-Origin-Free Formulation Using Optibumin 25 and PentaHibe Base

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EXECUTIVE SUMMARY This application note presents a defined, animal-origin-free (AOF) cryopreservation strategy addressing the limitations of high-DMSO and serum-derived components. The formulation—10% PentaHibe Base, 2% DMSO, and 4% Optibumin 25—was tested in CAR-T–mimicking workflows using healthy donor T cells. PentaHibe Base is a non-penetrating, carbohydrate-based cryoprotectant derived from pentaisomaltose, a patented subfraction of Dextran 1 …

Optiferrin – Guidelines for Use

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Download the Optiferrin® Guidelines for Use to learn how to prepare and apply InVitria’s recombinant human transferrin (rHTF) in serum-free and chemically defined media. This document includes detailed instructions for reconstitution, recommended concentrations for cell culture applications, storage and stability guidance, and regulatory notes. Optiferrin is a high-purity, animal-origin-free alternative to plasma-derived transferrin, supporting CHO, …

Lysobac – Guidelines for Use

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Download the Lysobac® Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant lysozyme. This animal-origin-free alternative to egg white lysozyme supports microbial control and reproducibility in chemically defined workflows.

ITSE+A – Guidelines for Use

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Download the ITSE+A Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant insulin, transferrin, selenium, and ethanolamine. Designed for xeno-free, defined workflows, it supports high-density culture in CHO, HEK, and stem cells.

ITSE AF – Guidelines for Use

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Download the ITSE Animal‑Free Guidelines for Use to learn preparation, recommended concentrations, storage, and applications. This recombinant supplement supports consistent growth and viability in serum‑free and chemically defined media for CHO, HEK293, and stem cell cultures.

ITS – Guidelines for Use

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Download the ITS Animal-Free Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant insulin, transferrin, and selenium. An animal-origin-free alternative to serum-derived supplements, it supports consistent growth across multiple cell types.

Exbumin – Guidelines for Use

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Download the Exbumin® Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant human albumin. As the first and only recombinant albumin approved as an excipient, Exbumin supports stability in vaccines, viral vectors, and cell therapies.

Optibumin 20 – Guidelines for Use

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Download the Optibumin 20 Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant HSA. High free‑thiol Cys‑34 content and 99% fatty‑acid‑free profile support small‑molecule solubilization, bioconjugation, and sensitive applications including iPSC, hESC, and IVF.

Lacromin – Guidelines for Use

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Download the Lacromin® Guidelines for Use to learn preparation, concentrations, storage, and applications of recombinant human lactoferrin. This animal-origin-free supplement supports CHO, HEK, pluripotent, and select primary cell cultures.