Month: June 2026

Functional Characterization of Lacromin® Recombinant Human Holo-Lactoferrin for Cell Culture and Advanced Therapy Applications

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Download App Note Here Executive Summary Lactoferrin (LF) is an iron-binding glycoprotein that is abundant in mammalian milk with established roles in iron homeostasis, anti-apoptotic protection, immune regulation, antimicrobial defense, antioxidant defense, neuroprotection, wound healing, and intestinal epithelial function. Lactoferrin exists in two forms: holo-lactoferrin (iron-saturated) and apo-lactoferrin (iron-free), with iron saturation influencing many of …

InVitria Joins NSF Engineering Research Center for Cell Manufacturing Technologies (CMaT)

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InVitria has joined the NSF Engineering Research Center for Cell Manufacturing Technologies (CMaT) as an industry member. The partnership brings together CMaT’s leadership in cell manufacturing research with InVitria’s expertise in animal-origin-free recombinant proteins to support consistent, scalable cell therapy manufacturing. CMaT works to transform the manufacture of cell-based therapeutics into large-scale, reproducible, and high-quality …

Improve Diagnostic Immunoassay Performance with Optibumin 25 Recombinant Human Serum Albumin

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EXECUTIVE SUMMARY Sensitive, reliable immunoassays are essential for early disease detection, where false-negative results can delay treatment. Albumin is commonly used in diagnostic immunoassays as a blocking agent and sample diluent, yet not all albumins perform the same. Aggregate populations present in conventional serum-derived albumins can scatter light and contribute to nonspecific background signal, elevating …

rHSA Improves Infectious Lentiviral Titer Yield During Tangential Flow Filtration by Passivating Filter Surfaces

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EXECUTIVE SUMMARY Infectious lentiviral titer is often lost during tangential flow filtration (TFF) in downstream processing due to shear and viral adsorption to filter membranes. Albumin is a known shear protectant and surface passivator that should address these mechanisms of loss. Bandiera et al. previously demonstrated that coating TFF membranes with plasma-derived human serum albumin …

Recombinant Albumin Improves Lentiviral Vector Recovery After Freeze-Thaw Stress

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EXECUTIVE SUMMARY Lentiviral vectors (LVVs) are widely used for gene delivery in cell and gene therapy workflows, but infectious titer can decline during downstream processing, storage, and freeze-thaw handling. Although cryopreservation at -80 °C is commonly used to limit thermal degradation, freeze-thaw stress can reduce LVV recovery through ice formation, osmotic stress, interfacial exposure, adsorption, …